The Foxes have defeated Stoke City, Brentford and Brighton & Hove Albion in the competition so far this term, while the Red Devils have overcome Watford, Liverpool and West Ham United.
Ahead of Sunday's visit of the 20-time champions of England, LCFC.com provides all you need to know...
How can I watch the game?
The last quarter-final of the round will be broadcast live on BBC One and the BBC iPlayer in the United Kingdom from 4:30pm on Sunday.
Who's starring on LCFC TV?
Three Leicester City legends will be on hand to share their views in the company of Dan Bates, with Matt Elliott and Iwan Roberts starring on the show, along with Gerry Taggart dialling in from the press box, starting at 3:30pm.
Beginning over four hours of comprehensive City coverage throughout the evening, Matchday Live is available on both LCFC TV and @LCFC social media.
Then, from approximately 4:50pm, join James Fielden and former Foxes defender Taggart, who will talk through the events as they unfold via live commentary on LCFC Radio. This can be accessed for free on the dedicated LCFC.com Match Centre.
Following the full-time whistle on Filbert Way, it's back to the studio for another 30 minutes of analysis from the panel, while we'll also, if time allows, hear from key figures from the Leicester City camp.
What's the officiating team?
Craig Pawson is the man in the middle on Filbert Way this Sunday, assisted by Simon Bennett and Harry Lennard. The fourth official will be Darren England. VAR, on the other hand, will be overseen by Stuart Attwell, alongside assistant Matthew Wilkes.
When does everything happen?
Sunday's clash is the second meeting between Leicester and United this term. Here's your schedule for the day...
| Event | Time |
| Matchday Live begins on LCFC TV | 3:30pm |
| Team news confirmed on @LCFC social media | 4pm |
| BBC One coverage commences* | 4:30pm |
| Commentary starts on LCFC Radio | 4:50pm |
| Kick-off | 5pm |
| Full-time | 6:45pm approx |
| Match of the Day: The FA Cup starts on BBC One* | 11:05pm |
| Highlights on LCFC TV & LCFC social media | 12pm (Monday) |
*UK only.
Who's in contention to play?
"[Ricardo Pereira] won’t be available for the weekend, but we’re pretty confident, after the international break, he’ll be okay," Brendan Rodgers said on Friday afternoon at LCFC Training Ground.
"It’s just a slight strain, but thankfully nothing too serious. Dennis [Praet] will be available for the weekend. On Cengo (Cengiz Ünder), we’ll see how he is after the international break."
What happened last time?
The two sides played out an entertaining 2-2 draw in the league fixture held at King Power Stadium on Boxing Day 2020.
The visitors twice went ahead via goals from Marcus Rashford and Bruno Fernandes, though the Foxes fought back through Harvey Barnes' effort and a late own goal from Axel Tuanzebe.
When can I catch match highlights?
Matchday highlights can be accessed on LCFC.com from midday the day following Emirates FA Cup ties - available for free to Digital Members on the Club's official website (free sign-up), while short clips will also be found on Leicester City's official social media channels.
Please note that in the interests of safety, Leicester City’s fixtures will continue to be played behind closed doors. To ensure matches can still go ahead and to help control the spread of COVID-19, the Football Club kindly asks its supporters to continue to follow their team from home and not to gather at any stadia.
All times GMT unless stated otherwise.