Papy Mendy starts in midfield alongside Danny Drinkwater, Ben Hamer starts in goal and Ben Chilwell makes his Champions League debut while Wes Morgan is the only player who started at the weekend.
On the bench is 18-year-old midfielder Harvey Barnes, who has scored three times in his last three Premier League 2 appearances.
SUBS: Sa, Boly, Neves, Evandro, Herrera, Layun, Pedro
CITY: Hamer; Hernández, Wasilewski, Morgan (c), Chilwell; Gray, Mendy, Drinkwater, Schlupp; Okazaki, Musa
SUBS: Albrighton, Amartey, Simpson, Zieler, Ulloa, Fuchs, Barnes