Matches are taking place in the USA, Canada and Mexico as nations bid to become world champions this summer and several of our own have taken to the pitch for their respective nations.
They include Harry Souttar, who captained the Socceroos to a 2-0 win over Turkey and a perfect start to the tournament, with a goal in either half from Nestory Irankunda and Connor Metcalfe confirming victory last Sunday morning.
The Leicester centre-half played the full game at BC Place in Vancouver, Canada, with the result leaving the Socceroos second in Group D with three points after the first round of fixtures.
They will face the hosts and current group leaders, USA, this Friday evening, an 8pm kick-off in Seattle.
In the early hours of Thursday morning, meanwhile, Abdul Fatawu emerged from the bench as Ghana claimed a dramatic FIFA World Cup victory over Panama. It looked to be heading for a goalless draw until Caleb Yirenkyi popped up with a goal five minutes into stoppage-time which saw Carlos Queiroz's men claim all three points in their opening Group L fixture.
Fatawu had started on the bench at Toronto Stadium but was called upon after 57 minutes with the scores still level, playing alongside departing Leicester City forward Jordan Ayew, who is captaining the Black Stars at the tournament.
The result sees the four-time African champions sit second in the group after matchday one, level on points with early leaders England, who they meet in Boston next Tuesday (9pm kick-off) after the Three Lions defeated Croatia 4-2 on Wednesday evening.
Bilal El Khannouss also got his World Cup campaign up and running, with the Morocco midfielder starting and playing 80 minutes in a 1-1 draw with Brazil.
Second in Group C, the Atlas Lions face Scotland, who lead the standings after a win against Haiti, at Boston Stadium tonight (Friday) in a 11pm kick-off.
All times BST.